COL18A1 Polyclonal Antibody | G-AB-01676

COL18A1 Polyclonal Antibody | G-AB-01676 | Gentaur Antibodies

Overview: This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Signal Transduction

Synonyms: Antiangiogenic agent, COIA1, Col18a1, Collagen alpha 1 (XVIII) chain, Collagen type XVIII alpha 1, Endostatin, KNO, KNO1, KS, Multi functional protein MFP

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_085059

Clonality: Polyclonal

Immunogen: Synthetic peptide of human COL18A1

Clone #:

Conjugation: Unconjugated

Swissprot: P39060

Santa Cruz: sc-16651/sc-25720

Calculated MW:

Observed MW:

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:100-1:300

Storage: Store at -20°C. Avoid freeze / thaw cycles.

COL18A1 Polyclonal Antibody DataSheet