CST3 Polyclonal Antibody | G-AB-01220
Gentaur Antibodies
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Gentaur Antibodies
CST3 Polyclonal Antibody | G-AB-01220
- SKU:
- G-AB-01220
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
CST3 Polyclonal Antibody | G-AB-01220 | Gentaur Antibodies
Overview: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins) , type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Cardiovascular, Stem Cells, Tags & Cell Markers
Synonyms: AD 8, AD8, Amyloid angiopathy and cerebral hemorrhage, ARMD11, bA218C14.4 (cystatin C) , bA218C14.4, Cst 3, Cst3, CST3 protein, Cystatin 3, Cystatin-3, Cystatin-C, Cystatin3, CystatinC, CYTC, Epididymis secretory protein Li 2, Gamma trace, Gamma-trace, HCCAA, HEL S 2, MGC117328, Neuroendocrine basic polypeptide, Post gamma globulin, Post-gamma-globulin
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP_000090
Clonality: Polyclonal
Immunogen: Synthetic peptide of human CST3
Clone #:
Conjugation: Unconjugated
Swissprot: P01034
Santa Cruz: sc-16989
Calculated MW: 16 kDa
Observed MW:
Concentration: 0.5 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: WB, IHC, ELISA
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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