CTTN Polyclonal Antibody | G-AB-08912
Gentaur Antibodies
- SKU:
- G-AB-08912
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
CTTN Polyclonal Antibody | G-AB-08912 | Gentaur Antibodies
Overview: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Signal Transduction
Synonyms: CTTN, EMS1, cortactin
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 2017
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human CTTN (NP_612632.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q14247
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC
Dilution: IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.