CTTN Polyclonal Antibody | G-AB-08912

CTTN Polyclonal Antibody | G-AB-08912 | Gentaur Antibodies

Overview: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: CTTN, EMS1, cortactin

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 2017

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CTTN (NP_612632.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q14247

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CTTN Polyclonal Antibody DataSheet