CYP3A5 Polyclonal Antibody | G-AB-11795

CYP3A5 Polyclonal Antibody | G-AB-11795 | Gentaur Antibodies

Overview: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms: CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 1577

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CYP3A5 (NP_000768.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P20815

Santa Cruz:

Calculated MW: 15 kDa/57 kDa

Observed MW: 68 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CYP3A5 Polyclonal Antibody DataSheet