DOK4 Polyclonal Antibody | G-AB-02273
Gentaur Antibodies
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Gentaur Antibodies
DOK4 Polyclonal Antibody | G-AB-02273
- SKU:
- G-AB-02273
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
DOK4 Polyclonal Antibody | G-AB-02273 | Gentaur Antibodies
Overview: Docking protein 4is aproteinthat in humans is encoded by theDOK4gene. Dok-4 is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation. Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Neuroscience, Signal Transduction
Synonyms: docking protein 4, Downstream of tyrosine kinase 4, FLJ10488, insulin receptor substrate 5, IRS5
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: BC001540
Clonality: Polyclonal
Immunogen: Recombinant protein of human DOK4
Clone #:
Conjugation: Unconjugated
Swissprot: Q8TEW6
Santa Cruz: sc-130133
Calculated MW:
Observed MW:
Concentration: 0.6 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: IHC, ELISA
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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