DOK4 Polyclonal Antibody | G-AB-02273

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$117.36 - $334.80
SKU:
G-AB-02273
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse
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DOK4 Polyclonal Antibody | G-AB-02273 | Gentaur Antibodies

Overview: Docking protein 4is aproteinthat in humans is encoded by theDOK4gene. Dok-4 is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation. Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience, Signal Transduction

Synonyms: docking protein 4, Downstream of tyrosine kinase 4, FLJ10488, insulin receptor substrate 5, IRS5

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC001540

Clonality: Polyclonal

Immunogen: Recombinant protein of human DOK4

Clone #:

Conjugation: Unconjugated

Swissprot: Q8TEW6

Santa Cruz: sc-130133

Calculated MW:

Observed MW:

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DOK4 Polyclonal Antibody DataSheet

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