DUSP12 Polyclonal Antibody | G-AB-08118

DUSP12 Polyclonal Antibody | G-AB-08118 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38) , which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: DUSP12, DUSP1, YVH1

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 11266

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human DUSP12 (NP_009171.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UNI6

Santa Cruz:

Calculated MW: 37 kDa

Observed MW: 36 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DUSP12 Polyclonal Antibody DataSheet