EPOR Polyclonal Antibody | G-AB-10221
Gentaur Antibodies
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Gentaur Antibodies
EPOR Polyclonal Antibody | G-AB-10221
- SKU:
- G-AB-10221
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
EPOR Polyclonal Antibody | G-AB-10221 | Gentaur Antibodies
Overview: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Immunology, Signal Transduction, Stem Cells
Synonyms: EPOR, EPO-R
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 2057
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human EPOR (NP_000112.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: P19235
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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