FH Polyclonal Antibody | G-AB-02501

FH Polyclonal Antibody | G-AB-02501 | Gentaur Antibodies

Overview: The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: FH, Fumarase, Fumarate hydratase, Fumarate hydratase mitochondrial, Fumarate hydratase, mitochondrial, FUMH, HLRCC, LRCC, MCL, MCUL 1, MCUL1, MS709, Multiple hereditary cutaneous leiomyomata

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC003108

Clonality: Polyclonal

Immunogen: Recombinant protein of human FH

Clone #:

Conjugation: Unconjugated

Swissprot: P07954

Santa Cruz: sc-100743

Calculated MW: 55 kDa

Observed MW:

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

FH Polyclonal Antibody DataSheet