FH Polyclonal Antibody | G-AB-10780

FH Polyclonal Antibody | G-AB-10780 | Gentaur Antibodies

Overview: The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: FH, FMRD, HLRCC, LRCC, MCL, MCUL1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 2271

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human FH (NP_000134.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P07954

Santa Cruz:

Calculated MW: 50 kDa/54 kDa

Observed MW: 50 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:10-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

FH Polyclonal Antibody DataSheet