FZD6 Polyclonal Antibody | G-AB-07403
Gentaur Antibodies
Write a Review
Gentaur Antibodies
FZD6 Polyclonal Antibody | G-AB-07403
- SKU:
- G-AB-07403
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Mouse, Rat
FZD6 Polyclonal Antibody | G-AB-07403 | Gentaur Antibodies
Overview: This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
Category Type: Polyclonal Antibody
Research Areas: Stem Cells
Synonyms: FZD6, FZ-6, FZ6, HFZ6, NDNC10
Reactivity: Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 8323
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human FZD6 (NP_003497.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: O60353
Santa Cruz:
Calculated MW: 75 kDa/79 kDa
Observed MW: 79 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB
Dilution: WB 1:1000-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Related Products
