FZD6 Polyclonal Antibody | G-AB-07403

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$218.00 - $465.00
SKU:
G-AB-07403
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Mouse, Rat
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FZD6 Polyclonal Antibody | G-AB-07403 | Gentaur Antibodies

Overview: This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.

Category Type: Polyclonal Antibody

Research Areas: Stem Cells

Synonyms: FZD6, FZ-6, FZ6, HFZ6, NDNC10

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 8323

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human FZD6 (NP_003497.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: O60353

Santa Cruz:

Calculated MW: 75 kDa/79 kDa

Observed MW: 79 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:1000-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

FZD6 Polyclonal Antibody DataSheet

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