IGF1R Polyclonal Antibody | G-AB-09571

IGF1R Polyclonal Antibody | G-AB-09571 | Gentaur Antibodies

Overview: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Developmental Biology, Signal Transduction

Synonyms: IGF1R, CD221, IGFIR, IGFR, JTK13

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3480

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human IGF1R (NP_000866.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P08069

Santa Cruz:

Calculated MW: 154 kDa

Observed MW: 90 kDa/140 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IGF1R Polyclonal Antibody DataSheet