IGF1R Polyclonal Antibody | G-AB-09571
- 3 to 5 Working Days
- Human, Mouse, Rat
IGF1R Polyclonal Antibody | G-AB-09571 | Gentaur Antibodies
Overview: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Developmental Biology, Signal Transduction
Synonyms: IGF1R, CD221, IGFIR, IGFR, JTK13
Reactivity: Human, Mouse, Rat
Gene ID: 3480
Immunogen: Recombinant fusion protein of human IGF1R (NP_000866.1) .
Calculated MW: 154 kDa
Observed MW: 90 kDa/140 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.