IkB alpha Polyclonal Antibody | G-AB-00111

IkB alpha Polyclonal Antibody | G-AB-00111 | Gentaur Antibodies

Overview: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction

Synonyms: I kappa B alpha, I-kappa-B-alpha, IkappaBalpha, IkB-alpha, IKBA, IKBA, IKBalpha, MAD 3, MAD3, NF kappa B inhibitor alpha, NFKBI, IKB alpha

Reactivity: Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Recombinant human NF-kappa-B inhibitor alpha protein

Clone #:

Conjugation: Unconjugated

Swissprot: P25963

Santa Cruz: sc-847, sc-371, sc-203

Calculated MW:

Observed MW:

Concentration: 2 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IkB alpha Polyclonal Antibody DataSheet