ITPR2 Polyclonal Antibody | G-AB-06030
Gentaur Antibodies
- SKU:
- G-AB-06030
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
ITPR2 Polyclonal Antibody | G-AB-06030 | Gentaur Antibodies
Overview: Inositol 1, 4, 5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC) , which convert phosphatidylinositol-4, 5 bisphosphate into IP3 and diacylglycerol (DAG) . The inositol 1, 4, 5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3) -gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Metabolism, Signal Transduction
Synonyms: 4, 5-trisphosphate receptor, Inositol 1 4 5 trisphosphate receptor type 2, Inositol 1, 4, 5-trisphosphate receptor type 2, Inositol 145 trisphosphate receptor type 2, InsP3 R2, InsP3R2, IP3 R2, IP3 receptor, IP3 receptor isoform 2, IP3R 2, IP3R2, ITPR 2, Itpr2, ITPR2, Type 2 inositol 1 4 5 trisphosphate receptor, Type 2 inositol 1, Type 2 inositol 145 trisphosphate receptor, Type 2 InsP3 receptor
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP002214
Clonality: Polyclonal
Immunogen: Synthetic peptide of human ITPR2
Clone #:
Conjugation: Unconjugated
Swissprot: Q14571
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1.74 mg/mL
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification method: Antigen affinity purification
Application: IHC, ELISA
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000
Storage: Store at -20°C. Avoid freeze / thaw cycles.