KLHL3 Polyclonal Antibody | G-AB-08435

KLHL3 Polyclonal Antibody | G-AB-08435 | Gentaur Antibodies

Overview: This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D) ; a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: KLHL3, PHA2D

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 26249

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human KLHL3 (NP_059111.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UH77

Santa Cruz:

Calculated MW: 55 kDa/61 kDa/64 kDa

Observed MW: 75 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

KLHL3 Polyclonal Antibody DataSheet