KLHL3 Polyclonal Antibody | G-AB-08435
Gentaur Antibodies
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Gentaur Antibodies
KLHL3 Polyclonal Antibody | G-AB-08435
- SKU:
- G-AB-08435
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
KLHL3 Polyclonal Antibody | G-AB-08435 | Gentaur Antibodies
Overview: This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D) ; a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Category Type: Polyclonal Antibody
Research Areas:
Synonyms: KLHL3, PHA2D
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID: 26249
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human KLHL3 (NP_059111.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q9UH77
Santa Cruz:
Calculated MW: 55 kDa/61 kDa/64 kDa
Observed MW: 75 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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