LEP Polyclonal Antibody | G-AB-08003

LEP Polyclonal Antibody | G-AB-08003 | Gentaur Antibodies

Overview: This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction, Stem Cells

Synonyms: LEP, LEPD, OB, OBS, leptin

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3952

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human LEP (NP_000221.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P41159

Santa Cruz:

Calculated MW: 18 kDa

Observed MW: 17 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

LEP Polyclonal Antibody DataSheet