Lep Polyclonal Antibody | G-AB-00094
- 3 to 5 Working Days
Lep Polyclonal Antibody | G-AB-00094 | Gentaur Antibodies
Overview: Leptin is a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. Leptin is the most critical hormone in the homeostatic regulation of energy balance among those so far discovered. Leptin primarily acts on the neurons of the mediobasal part of hypothalamus to regulate food intake, thermogenesis, and the blood glucose level. Leptin also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. Leptin has also been linked to type 2 diabetes mellitus development.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction, Stem cells
Synonyms: FLJ94114, LEP, LEP, LEPD, Leptin (murine obesity homolog) , Leptin (obesity homolog, mouse) , Leptin, Leptin Murine Obesity Homolog, Leptin Precursor Obesity Factor, OB, Obese protein, Obese, mouse, Obesity, Obesity factor, Obesity homolog, Obesity Murine Homolog Leptin, OBS, OTTHUMP00000212285
Accession #: 25068
Immunogen: Recombinant Rat Leptin protein
Santa Cruz: sc-48408, sc-9014, sc-843, sc-842
Concentration: 2 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.