MAGEL2 Polyclonal Antibody | G-AB-01767

MAGEL2 Polyclonal Antibody | G-AB-01767 | Gentaur Antibodies

Overview: Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN) , a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: Mage-l2, MAGE-like 2, MAGE-like protein 2, MAGEL2, melanoma antigen-like gene 2, NDNL1, Necdin like protein 1, necdin-like 1, nM15, ns7, Protein nM15, PWLS

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_061939

Clonality: Polyclonal

Immunogen: Synthetic peptide of human MAGEL2

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UJ55

Santa Cruz: sc-164952/sc-164951

Calculated MW:

Observed MW:

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MAGEL2 Polyclonal Antibody DataSheet