MCAM Polyclonal Antibody | G-AB-08489

MCAM Polyclonal Antibody | G-AB-08489 | Gentaur Antibodies

Overview: CD146, also known as melanoma cell adhesion molecule (MCAM) or MUC18, originally identified as a biomarker of melanoma progression, is a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily . Structurally, it consists of five Ig domains, a transmembrane domain, and a cytoplasmic region. In normal adult tissue, CD146 is primarily expressed by vascular endothelium and smooth muscle. CD146 is a key cell adhesion protein in vascular endothelial cell activity and angiogenesis, and has been used as marker of circulating endothelium cells (CECs) .

Category Type: Polyclonal Antibody

Research Areas: Immunology, Signal Transduction, Cancer, Stem Cells, Cardiovascular

Synonyms: MCAM, CD146, MUC18

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4162

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MCAM (NP_006491.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P43121

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MCAM Polyclonal Antibody DataSheet