MCAM Polyclonal Antibody | G-AB-08489
Gentaur Antibodies
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Gentaur Antibodies
MCAM Polyclonal Antibody | G-AB-08489
- SKU:
- G-AB-08489
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
MCAM Polyclonal Antibody | G-AB-08489 | Gentaur Antibodies
Overview: CD146, also known as melanoma cell adhesion molecule (MCAM) or MUC18, originally identified as a biomarker of melanoma progression, is a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily . Structurally, it consists of five Ig domains, a transmembrane domain, and a cytoplasmic region. In normal adult tissue, CD146 is primarily expressed by vascular endothelium and smooth muscle. CD146 is a key cell adhesion protein in vascular endothelial cell activity and angiogenesis, and has been used as marker of circulating endothelium cells (CECs) .
Category Type: Polyclonal Antibody
Research Areas: Immunology, Signal Transduction, Cancer, Stem Cells, Cardiovascular
Synonyms: MCAM, CD146, MUC18
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 4162
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human MCAM (NP_006491.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: P43121
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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