MSH4 Polyclonal Antibody | G-AB-02074

MSH4 Polyclonal Antibody | G-AB-02074 | Gentaur Antibodies

Overview: This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: hMSH4, MSH 4, MSH4, MSH4, MutS homolog 4 (E. Coli) , MutS homolog 4, MutS protein homolog 4

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC033030

Clonality: Polyclonal

Immunogen: Recombinant protein of human MSH4

Clone #:

Conjugation: Unconjugated

Swissprot: O15457

Santa Cruz: sc-69510/sc-69512

Calculated MW:

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:100-1:300

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MSH4 Polyclonal Antibody DataSheet