MSH4 Polyclonal Antibody | G-AB-12267

(No reviews yet) Write a Review
$218.00 - $465.00
SKU:
G-AB-12267
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
Adding to cart… The item has been added

MSH4 Polyclonal Antibody | G-AB-12267 | Gentaur Antibodies

Overview: This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: MSH4

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4438

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MSH4 (NP_002431.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: O15457

Santa Cruz:

Calculated MW: 104 kDa

Observed MW: 105 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MSH4 Polyclonal Antibody DataSheet