p53 Polyclonal Antibody | G-AB-10837

p53 Polyclonal Antibody | G-AB-10837 | Gentaur Antibodies

Overview: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277) .

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms: TP53, BCC7, LFS1, P53, TRP53, Trp53, bbl, bfy, bhy, p44, p53, Tp53

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 22059

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of mouse p53 (NP_035770.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P02340

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:10-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

p53 Polyclonal Antibody DataSheet