PC Polyclonal Antibody | G-AB-11015

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$218.00 - $465.00
SKU:
G-AB-11015
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
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PC Polyclonal Antibody | G-AB-11015 | Gentaur Antibodies

Overview: This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: PC, PCB

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5091

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PC (NP_001035806.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P11498

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:10-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PC Polyclonal Antibody DataSheet