PC Polyclonal Antibody | G-AB-11015
Gentaur Antibodies
- SKU:
- G-AB-11015
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
PC Polyclonal Antibody | G-AB-11015 | Gentaur Antibodies
Overview: This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Metabolism, Signal Transduction
Synonyms: PC, PCB
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 5091
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human PC (NP_001035806.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: P11498
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IF
Dilution: IF 1:10-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.