Phospho-CDK6 (Y13) Polyclonal Antibody | G-AB-12551

Phospho-CDK6 (Y13) Polyclonal Antibody | G-AB-12551 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms: CDK6, MCPH12, PLSTIRE

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 1021

Accession #:

Clonality:

Immunogen: A phospho specific peptide corresponding to residues surrounding Y13 of human CDK6

Clone #:

Conjugation: Unconjugated

Swissprot: Q00534

Santa Cruz:

Calculated MW: 36 kDa

Observed MW: 37 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-CDK6 (Y13) Polyclonal Antibody DataSheet