Phospho-Dnmt1 (pS714) Polyclonal Antibody | G-AB-12480
Gentaur Antibodies
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Gentaur Antibodies
Phospho-Dnmt1 (pS714) Polyclonal Antibody | G-AB-12480
- SKU:
- G-AB-12480
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
Phospho-Dnmt1 (pS714) Polyclonal Antibody | G-AB-12480 | Gentaur Antibodies
Overview: This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT, m.HsaI, DNMT1
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID: 1786
Accession #:
Clonality:
Immunogen: A synthetic phosphorylated peptide around S714 of human Dnmt1 (NP_001370.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: P26358
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IF
Dilution: IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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