DNMT1 Polyclonal Antibody | G-AB-09557
Gentaur Antibodies
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Gentaur Antibodies
DNMT1 Polyclonal Antibody | G-AB-09557
- SKU:
- G-AB-09557
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
DNMT1 Polyclonal Antibody | G-AB-09557 | Gentaur Antibodies
Overview: This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT, m.HsaI, DNMT1
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 1786
Accession #:
Clonality:
Immunogen: A synthetic peptide of human DNMT1.
Clone #:
Conjugation: Unconjugated
Swissprot: P26358
Santa Cruz:
Calculated MW: 144 kDa/183 kDa/184 kDa
Observed MW: 230 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC
Dilution: WB 1:500-1:2000 IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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