Phospho-EIF4EBP1 (T36) Polyclonal Antibody | G-AB-12554

Phospho-EIF4EBP1 (T36) Polyclonal Antibody | G-AB-12554 | Gentaur Antibodies

Overview: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) , which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism

Synonyms: 4E-BP1, 4EBP1, BP-1, PHAS-I, EIF4EBP1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 1978

Accession #:

Clonality:

Immunogen: A phospho specific peptide corresponding to residues surrounding T36 of human EIF4EBP1

Clone #:

Conjugation: Unconjugated

Swissprot: Q13541

Santa Cruz:

Calculated MW: 12 kDa

Observed MW: 20 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-EIF4EBP1 (T36) Polyclonal Antibody DataSheet