Phospho-P70S6K1 (T389) Polyclonal Antibody | G-AB-12616

Phospho-P70S6K1 (T389) Polyclonal Antibody | G-AB-12616 | Gentaur Antibodies

Overview: This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms: PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70 (S6K) -alpha, p70-S6K, p70-alpha, P70 S6K, RPS6KB1, p70S6KA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 6198

Accession #:

Clonality:

Immunogen: A phospho synthetic peptide corresponding to residues surrounding T389 of human P70S6K1.

Clone #:

Conjugation: Unconjugated

Swissprot: P23443

Santa Cruz:

Calculated MW: 59 kDa

Observed MW: 85 kDa/90 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-P70S6K1 (T389) Polyclonal Antibody DataSheet