Phospho-P70S6K1 (T389) Polyclonal Antibody | G-AB-12616
- 3 to 5 Working Days
- Human, Mouse, Rat
Phospho-P70S6K1 (T389) Polyclonal Antibody | G-AB-12616 | Gentaur Antibodies
Overview: This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction
Synonyms: PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70 (S6K) -alpha, p70-S6K, p70-alpha, P70 S6K, RPS6KB1, p70S6KA
Reactivity: Human, Mouse, Rat
Gene ID: 6198
Immunogen: A phospho synthetic peptide corresponding to residues surrounding T389 of human P70S6K1.
Calculated MW: 59 kDa
Observed MW: 85 kDa/90 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.