Phospho-SNCA (S129) Polyclonal Antibody | G-AB-12567

Phospho-SNCA (S129) Polyclonal Antibody | G-AB-12567 | Gentaur Antibodies

Overview: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Neuroscience

Synonyms: PD1, NACP, PARK1, PARK4, SNCA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 6622

Accession #:

Clonality:

Immunogen: A phospho specific peptide corresponding to residues surrounding S129 of human SNCA

Clone #:

Conjugation: Unconjugated

Swissprot: P37840

Santa Cruz:

Calculated MW: 11 kDa/13 kDa/14 kDa

Observed MW: 20 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-SNCA (S129) Polyclonal Antibody DataSheet