Phospho-Histone H2A (S129) Polyclonal Antibody | G-AB-12618
- 3 to 5 Working Days
- Human, Rat
Phospho-Histone H2A (S129) Polyclonal Antibody | G-AB-12618 | Gentaur Antibodies
Overview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Category Type: Phosphorylated antibody
Synonyms: H2A1, SPT11
Reactivity: Human, Rat
Gene ID: 851811
Immunogen: A phospho synthetic peptide corresponding to residues surrounding S129 of human Histone H2A.
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.