PRKCZ Polyclonal Antibody | G-AB-08595
Gentaur Antibodies
- SKU:
- G-AB-08595
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
PRKCZ Polyclonal Antibody | G-AB-08595 | Gentaur Antibodies
Overview: Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Signal Transduction
Synonyms: PRKCZ, PKC-ZETA, PKC2
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 5590
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human PRKCZ (NP_002735.3) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q05513
Santa Cruz:
Calculated MW: 46 kDa/56 kDa/67 kDa
Observed MW: 78 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.