PRKCZ Polyclonal Antibody | G-AB-08595

PRKCZ Polyclonal Antibody | G-AB-08595 | Gentaur Antibodies

Overview: Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: PRKCZ, PKC-ZETA, PKC2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5590

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PRKCZ (NP_002735.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q05513

Santa Cruz:

Calculated MW: 46 kDa/56 kDa/67 kDa

Observed MW: 78 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PRKCZ Polyclonal Antibody DataSheet