RBL2 Polyclonal Antibody | G-AB-04707
Gentaur Antibodies
Write a Review
Gentaur Antibodies
RBL2 Polyclonal Antibody | G-AB-04707
- SKU:
- G-AB-04707
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
RBL2 Polyclonal Antibody | G-AB-04707 | Gentaur Antibodies
Overview: Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling
Synonyms: 130 kDa retinoblastoma associated protein, 130 kDa retinoblastoma-associated protein, IB4, p130, PPAR-alpha-interacting complex protein 128, PRB2, Rb2, Rbl2, RBL2, RBR 2, RBR-2, RBR2, Retinoblastoma like 2, Retinoblastoma-like protein 2, Retinoblastoma-related protein 2, RIC128
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP005602
Clonality: Polyclonal
Immunogen: Synthetic peptide of human RBL2
Clone #:
Conjugation: Unconjugated
Swissprot: Q08999
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 0.8 mg/mL
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification method: Antigen affinity purification
Application: IHC, ELISA
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Related Products
