SMG8 Polyclonal Antibody | G-AB-01425
Gentaur Antibodies
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Gentaur Antibodies
SMG8 Polyclonal Antibody | G-AB-01425
- SKU:
- G-AB-01425
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
SMG8 Polyclonal Antibody | G-AB-01425 | Gentaur Antibodies
Overview: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC) . Acts as a regulator of kinase activity.
Category Type: Polyclonal Antibody
Research Areas: Cancer
Synonyms: ABC 2, ABC2, Amplified in breast cancer gene 2 protein, Chromosome 17 open reading, chromosome 17 open reading frame 71, FLJ10587, Protein smg 8 homolog, protein SMG8, SMG8, SMG8 protein
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP_060619
Clonality: Polyclonal
Immunogen: Synthetic peptide of human SMG8
Clone #:
Conjugation: Unconjugated
Swissprot: Q8ND04
Santa Cruz: sc-240063
Calculated MW:
Observed MW:
Concentration: 0.3 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: IHC, ELISA
Dilution: IHC 1:25-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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