SMG8 Polyclonal Antibody | G-AB-01425

(No reviews yet) Write a Review
$117.36 - $334.80
SKU:
G-AB-01425
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse
Adding to cart… The item has been added

SMG8 Polyclonal Antibody | G-AB-01425 | Gentaur Antibodies

Overview: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC) . Acts as a regulator of kinase activity.

Category Type: Polyclonal Antibody

Research Areas: Cancer

Synonyms: ABC 2, ABC2, Amplified in breast cancer gene 2 protein, Chromosome 17 open reading, chromosome 17 open reading frame 71, FLJ10587, Protein smg 8 homolog, protein SMG8, SMG8, SMG8 protein

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_060619

Clonality: Polyclonal

Immunogen: Synthetic peptide of human SMG8

Clone #:

Conjugation: Unconjugated

Swissprot: Q8ND04

Santa Cruz: sc-240063

Calculated MW:

Observed MW:

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:25-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SMG8 Polyclonal Antibody DataSheet

Related Products