SOCS1 Polyclonal Antibody | G-AB-02858

SOCS1 Polyclonal Antibody | G-AB-02858 | Gentaur Antibodies

Overview: This gene encodes a member of the STAT-induced STAT inhibitor (SSI) , also known as suppressor of cytokine signaling (SOCS) , family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO) , CSF2/GM-CSF, and interferon (IFN) -gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction

Synonyms: CISH 1, CISH1, Cytokine inducible SH2 protein 1, JAB, JAK binding protein, JAK-binding protein, Janus kinase binding protein, SOCS 1, SOCS-1, Socs1, SOCS1, SSI 1, SSI-1, SSI1, STAT induced STAT inhibitor 1, STAT-induced STAT inhibitor 1, Suppressor of cytokine signaling 1, Supressor of cytokine signalling 1, TEC interacting protein 3, Tec-interacting protein 3, TIP 3, TIP-3, TIP3

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_003736

Clonality: Polyclonal

Immunogen: Synthetic peptide of human SOCS1

Clone #:

Conjugation: Unconjugated

Swissprot: O15524

Santa Cruz: sc-7006/sc-9021

Calculated MW: 24 kDa

Observed MW:

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:100-1:300

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SOCS1 Polyclonal Antibody DataSheet