SOST Polyclonal Antibody | G-AB-12095
Gentaur Antibodies
- SKU:
- G-AB-12095
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
SOST Polyclonal Antibody | G-AB-12095 | Gentaur Antibodies
Overview: Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
Category Type: Polyclonal Antibody
Research Areas:
Synonyms: SOST, CDD, DAND6, SOST1, VBCH
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID: 50964
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human SOST (NP_079513.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q9BQB4
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC
Dilution: IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.