UNC13B Polyclonal Antibody | G-AB-09187
Gentaur Antibodies
- SKU:
- G-AB-09187
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
UNC13B Polyclonal Antibody | G-AB-09187 | Gentaur Antibodies
Overview: This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
Category Type: Polyclonal Antibody
Research Areas: Neuroscience, Signal Transduction
Synonyms: UNC13B, MUNC13, UNC13, Unc13h2
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID: 10497
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human UNC13B (NP_006368.3) .
Clone #:
Conjugation: Unconjugated
Swissprot: O14795
Santa Cruz:
Calculated MW: 180 kDa/182 kDa
Observed MW: 210 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IF
Dilution: WB 1:500-1:2000 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.