UNC13B Polyclonal Antibody | G-AB-09187

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€183.12 - €390.60
SKU:
G-AB-09187
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse
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UNC13B Polyclonal Antibody | G-AB-09187 | Gentaur Antibodies

Overview: This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience, Signal Transduction

Synonyms: UNC13B, MUNC13, UNC13, Unc13h2

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 10497

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human UNC13B (NP_006368.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: O14795

Santa Cruz:

Calculated MW: 180 kDa/182 kDa

Observed MW: 210 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

UNC13B Polyclonal Antibody DataSheet