Vimentin Polyclonal Antibody | G-AB-05240

Vimentin Polyclonal Antibody | G-AB-05240 | Gentaur Antibodies

Overview: Vimentin, also named as VIM, belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha (TNFA; 191160) and inhibited by the antiinflammatory cytokine IL10 (124092) , suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein, 55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Developmental Biology, Neuroscience, Signal Transduction, Stem Cells

Synonyms: CTRCT30, Epididymis luminal protein 113, FLJ36605, HEL113, VIM, VIME, Vimentin

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse vimentin

Clone #:

Conjugation: Unconjugated

Swissprot: P08670, P20152, P31000

Santa Cruz:

Calculated MW: 57 kDa

Observed MW: 57 kDa

Concentration: 1.1 mg/mL

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000, IHC 1:200-1:800

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Vimentin Polyclonal Antibody DataSheet