XPC Polyclonal Antibody | G-AB-06988

XPC Polyclonal Antibody | G-AB-06988 | Gentaur Antibodies

Overview: The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER) . The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: DNA repair protein complementing XP C cells, DNA repair protein complementing XP-C cells, DNA repair protein complementing XPC cells, p125, RAD4, Xeroderma pigmentosum complementation group C, Xeroderma pigmentosum group C complementing protein, Xeroderma pigmentosum group C protein, Xeroderma pigmentosum group C-complementing protein, Xeroderma pigmentosum group III, XP 3, XP C, XP group C, XP3, Xpc, XPC gene, XPC, XPCC

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP004619

Clonality: Polyclonal

Immunogen: Synthetic peptide of human XPC

Clone #:

Conjugation: Unconjugated

Swissprot: Q01831

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.66 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

XPC Polyclonal Antibody DataSheet