XPC Polyclonal Antibody | G-AB-12154

XPC Polyclonal Antibody | G-AB-12154 | Gentaur Antibodies

Overview: This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: XPC, RAD4, XP3, XPCC, p125

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 7508

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human XPC (NP_004619.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q01831

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

XPC Polyclonal Antibody DataSheet