AANAT Polyclonal Antibody | G-AB-00824

AANAT Polyclonal Antibody | G-AB-00824 | Gentaur Antibodies

Overview: The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Neuroscience

Synonyms: AA-NAT, Aanat, Aralkylamine N-acetyltransferase, Arylalkylamine N acetyltransferase, Serotonin acetylase, Serotonin N-acetyltransferase, SNAT, SNAT

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC069434

Clonality: Polyclonal

Immunogen: Recombinant protein of human AANAT

Clone #:

Conjugation: Unconjugated

Swissprot: Q16613

Santa Cruz: sc-55612/sc-68346

Calculated MW:

Observed MW:

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

AANAT Polyclonal Antibody DataSheet