AANAT Polyclonal Antibody | G-AB-00824
- 3 to 5 Working Days
- Human, Mouse, Rat
AANAT Polyclonal Antibody | G-AB-00824 | Gentaur Antibodies
Overview: The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Metabolism, Neuroscience
Synonyms: AA-NAT, Aanat, Aralkylamine N-acetyltransferase, Arylalkylamine N acetyltransferase, Serotonin acetylase, Serotonin N-acetyltransferase, SNAT, SNAT
Reactivity: Human, Mouse, Rat
Accession #: BC069434
Immunogen: Recombinant protein of human AANAT
Santa Cruz: sc-55612/sc-68346
Concentration: 0.6 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: IHC, ELISA
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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